Publications

By Zora Scientists

2009


Ejsing CS, Sampaio JL, Surendranath V, Duchoslav E, Ekroos K, Klemm RW, Simons K, Shevchenko A.			Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry	Proc Natl Acad Sci USA. 2009 Jan 27. [Epub ahead of print]

Ståhlman M, Ejsing CS, Tarasov K, Perman J, Borén J, Ekroos K.			High-Throughput Shotgun Lipidomics by Quadrupole Time-of-Flight Mass Spectrometry	Journal of Chromatography B. 2009 [Epub ahead of print]

Sergent O, Ekroos K, Lefeuvre-Orfila L, Rissel M, Forsberg G-B, Oscarsson J, Andersson TB,Lagadic-Gossmann D.			Ximelagatran increases membrane fluidity and changes membrane lipid composition in primary human hepatocytes	Toxicology in Vitro, 2009 Jul 16. [Epub ahead of print]

2008

Ekroos, K.	Unraveling glycerophospholipidomes by lipidomics, in “Biomarker methods in drug discovery and development, Methods in pharmacology and toxicology”	Humana Press, 2008.

Tarassov K, Messier V, Landry CR, Radinovic S, Molina MM, Shames I, Malitskaya Y, Vogel J, Bussey H, Michnick SW.	An in Vivo Map of the Yeast Protein Interactome	Science (2008); 320: 1465-1470.

Orešič M, Simell S, Sysi-Aho M, Näntö-Salonen K, Seppänen-Laakso T. et al.	Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes	JEM (2008) 205, No. 13, 2975-2984.

Jänis MT, Laaksonen R, Orešič M.	Metabolomic strategies to identify tissue-specific effects of cardiovascular drugs	Expert Opin. Drug Metab. Toxicol. (2008) 4(6):665-680.

2007

Lelliott CJ, Ljungberg A, Ahnmark A, William-Olsson L, Ekroos K, Elmgren A, Arnerup G, Shoulders CC, Oscarsson J, Lindén D.	Hepatic PGC-1β over-expression induces combined hyperlipidemia and modulates the response to PPARα Activation.	Arterioscler Thromb Vasc Biol. (2007) 27, 2707-2713.

Schick B, Laaksonen R, Frohlich J, Päivä H, Lehtimäki T, Humphries KH, Côté H.	Decreased skeletal muscle mitochondrial DNA in patients treated with high-dose simvastatin	Clin Pharmacol Ther (2007);81(5):650-3.

2006

Lindén D, William-Olsson L, Ahnmark A, Ekroos K, Hallberg C, Peilot-Sjögren H, Becker B, Svensson L, Clapham JC, Oscarsson J, Schreyer S.	Liver directed overexpression of mithocondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triglyceride secretion and reduced fatty acid oxidation	FASEB J. 20(3):434-43 (2006).

Laaksonen R, Katajamaa M, Päivä H, Sysi-Aho M, Saarinen L, Junni P, Lütjohann D, Smet J, Van Coster R, Seppänen-Laakso T, Lehtimäki T, Soini J, Orešič M.	A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin induced changes in muscle	PLoS ONE 1(1): e97 (2006).

Eising CS, Duchoslav E, Sampaio J, Simons K, Bonner R, Thiele C, Ekroos K, Shevchenko A.	Automated identification and quantification of glycerophospholipid molecular species by multiple precursor ion scanning	Anal Chem. (2006) Sep 1;78(17):6202-14.

Campbell-Valois FX, Tarassov K, Michnick SW.	Massive sequence perturbation of the Raf ras binding domain reveals relationships between sequence conservation, secondary structure propensity, hydrophobic core organization and stability	J Mol Biol. 8;362(1):151-71(2006).

2005

Kuerschner L, Ejsing SC, Ekroos K, Shevchenko A, Anderson KI, Thiele C.			Polyene-lipids: A new tool to image lipids	Nature Methods (2005); 2, 39 – 45.

Campbell-Valois FX, Tarassov K, Michnick SW.			Massive sequence perturbation of a small protein	Proc Natl Acad Sci USA. (2005);102(42):14988-93.

Tarassov K, Michnick SW.			iVici: Interrelational Visualization and Correlation Interface	Genome Biol. 2005;6(13):R115. Epub 2005 Dec 30.

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